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Price and Availability:

Please contact us for prices and availability on any of The Native Antigen Company range of products.

 

Antigens, antibodies and immunoassays

The Native Antigen Company (NAC) specialises in development and manufacture of native and recombinant viral and bacterial antigens, antibodies and related products. NAC’s products are used by pharmaceutical and IVD manufacturers in vaccine research and serology where proper folding and glycosylation are vital. As well as offering antigens from a rapidly expanding portfolio, NAC undertakes bespoke product development and custom manufacture using its proprietary mammalian cell protein expression system.

Seasonal Influenza Vaccine Antigens

In February and September of each year, the World Health Organization (WHO) convenes with its network of advisors to decide on flu vaccine formulations for the northern and southern hemispheres, respectively. To support vaccine research and development, The Native Antigen Company has developed Haemagglutinin (HA) and Neuraminidase (NA) antigens for the WHO-recommended egg-based and recombinant vaccine strains. Available in bulk quantities, antigens can be used in a range of applications, including immunoassay development and as immunogens.

NOW AVAILABLE! 2024 Influenza Antigens For Southern Hemisphere Flu Season.

Visit The Native Antigen website for the full list of Seasonal Influenza Antigens.

Vector-Borne Diseases

Flaviviruses infect up to 400 million people yearly, causing a spectrum of disorders, which, in severe cases, are often fatal. A vaccine is not yet available for most flavivirus diseases hence, vector control and accessible, reliable diagnostics are central to limiting the spread of those arboviral infections. The flavivirus vectors include different species that spread worldwide, highlighting their pandemic potential. The order Bunyaviridae includes segmented negative-strand RNA viruses, which pose a high risk of outbreaks due to their capability for rapid reassortment. This risk is evidenced by the many diseases they cause in humans, and they are spread by various arthropod, mammal, or rodent vectors.

Human Coronavirus Product Update

Coronavirus Reagents available from The Native Antigen CompanyThe Native Antigen Company has an extensive range of antigens and antibodies for research into the range of human coronaviruses, including SARS-CoV-2 (better known as the disease COVID-19). If there is a product not current under development by The Native Antigen Company, then please either contact ourselves or The Native Antigen Company directly, as they may be able to develop it for you.

Please follow the links below for the latest information on the currently available human coronavirus products and for information on the human coronavirus products in the development pipeline:

The Native Antigen Company is developing an extensive range of antigens and antibodies for the human coronaviruses, including SARS-CoV-2 disease, (COVID-19).

Human coronovirus development pipeline

To support the investigation of SARS-CoV-2 variants, The Native Antigen Company offers a growing range of mutant Spike antigens. Expressed from our proprietary mammalian expression system, these antigens display full glycosylation and proper folding for use in the development of high-performance assays and other applications.

Human coronavirus mutant spike antigen development pipeline

Currently available human coronavirus products: antigens or antibodies

The following bacterial, protozoan and viral antigens are available:

Antigens: There are now over 60 species of bacterial, protozoan and viral antigens available from NAC and throughout the range, there are often multiple antigens per species. For example, there are 5 CMV antigens available.

Adenovirus
Astrovirus
Bordetella pertussis
Borrelia
Campylobacter
Candida albicans
Chikungunya Virus
Chlamydia
Clostridium
CMV
Corynebacterium diphtheriae
Crimean Congo Hemorrhagic Fever Virus
Dengue Virus
Ebola Virus
Echinococcus
Enterovirus
Epstein Barr Virus
Hantavirus
Helicobacter pylori
Hepatitis B virus
Hepatitis C virus
Hepatitis E
HSV
Human Coronavirus
Human Immunodeficiency Virus
Human Metapneumovirus
Human Parainfluenza Virus
Influenza virus
Japanese Encephalitis Virus
Lassa Fever Virus
Legionella
Leptospira
Marburg Virus
Mayaro Virus
Measles virus
Mumps virus
Mycoplasma
Neisseria gonorrhoeae
Nipah Virus
Norovirus
O’nyong’nyong Virus
Oropouche virus
Parvovirus
Plasmodium
Powassan Virus
Puumala VirusRespiratory Syncytial Virus
Rhinovirus
Rift Valley Fever Virus
Ross River Virus
Rotavirus
Rubella virus
Saint Louis encephalitis virus
Salmonella
Severe Fever with Thrombocytopenia Virus
Streptococcus pneumoniae
Tick-Borne Encephalitis Virus
Toscana virus
Toxoplasma gondii
Trichomonas
Usutu Virus
Vaccinia Virus
Varicella-Zoster Virus
Vibrio cholerae
Wesselsbron virus
West Nile Virus
Yellow Fever Virus
Zika Virus

The following antibodies are available:

Antibodies: The Native Antigen Company have now developed a high quality range of antibodies that have been carefully tested alongside their antigens, thus providing customers with all of the key components required for immunoassay development and manufacturing. For many of the bacterial, protozoan and viral antibodies, there are multiple antibodies available. For example there are 8 Clostridium difficile antibodies available.

Adenovirus
Astrovirus
Borrelia burgdorferi
Campylobacter
Chikungunya Virus
Chlamydia
Clostridium
CMV
Corynebacterium diphtheriae
Diphtheria toxin
Dengue Virus
Ebola Virus
Escherichia coli
Giardia
Hantavirus
Hepatitis A Virus
HSVHepatitis B Virus
Hepatitis C Virus
Human Metapneumovirus
Human Papilloma Virus
Influenza Virus
IgG’s (human, mouse, rabbit, sheep)
IgM (human)
Japanese Encephalitis Virus
Legionella pneumophilia
Listeria monocytogenes
Metapneumovirus
Mycoplasma pneumoniae
Nipah Virus
Norovirus
O’nyong’nyong Virus
Powassan VirusRespiratory Syncytial Virus
Rotavirus
Rubella Virus
Salmonella typhi
Salmonella paratyphi
SARS Coronavirus Nuclearprotein
Staphylococcus aureus enterotoxin
Streptococcus pneumoniae
Tenus toxin
Tick-borne Encephalitis Virus
Toscana Virus
Toxoplasma gondii
Vibrio cholerae
West Nile Virus
Yellow Fever Virus
Zika Virus

 

Other Products:

The in addition the extensive range of antigens and antibodies, The Native Antigen Company has introduced a number of new products:

  • Virus Like Particles (VLP)
  • Toxins
  • ELISA Kits – Borrelia burgdorferi IgG, Borrelia burgdorferi IgM, Tick-borne encephalitis Virus IgG, Tick-borne encephalitis Virus IgM, Zika Virus IgG/IgM/IgA, Zika virus IgM and Zika Virus NS1 Capture (in development – Dengue Virus IgG, Dengue Virus IgM and Dengue Virus IgM μ-capture)
  • Accessory Reagents – including donor sera, isotype controls and secondary antibodies.
 
  • Virus Receptors – MXRA8 Protein (Human) (in development – CLEC4M (Human), DC-Sign (Human), Ephrin B2 (Human), MOG Protein (Human), Neuropilin 2 Protein (Human) and Tyrosine-Protein Kinase Receptor UFO (Human)).
  • Veterinary Reagents
  • Conjugation and Labelling kits
  • Matched Antibody Pairs