flashBAC™ is a one step high throughput Baculovirus based protein expression platform
flashBAC™ Baculovirus Expression System
When it comes to recombinant protein production there are several variants of the flashBAC baculovirus expression technology available. Each of our flashBAC categories contain different genetic modifications with the purpose of increasing protein yields for specific protein targets. For secreted and membrane targeted proteins try GOLD or ULTRA and for intracellular VLPs we recommend PRIME.
- flashBAC™ – Original, good for general purpose expression
- flashBACGOLD – Chitinase and cathepsin genes deleted, ideal for secreted proteins
- flashBACULTRA – Lacks non essential genes to enhance cell stability late in infection
- flashBACPRIME – Essentially a wild-type genome, superior for producing some VLP’s
The flashBAC technology is also highly flexible thanks to its compatibility with a wide variety of transfer vectors.
What is the flashBAC™ Baculovirus Expression System?
The flashBAC expression system utilises DNA from the baculovirus genome that has been genetically optimized to function as a recombinant protein expression vector. The system offers high yields of quality protein, is easy to use and is also back compatible with most transfer vectors based on homologous recombination. In this way the flashBAC™ system has become the expression of choice for those needing optimal protein expression in insect cells, and increasingly in mammalian cells via the BacMAM system. The genetic modifications not only prevent parental virus from replicating but also optimise the expression of difficult to express proteins.